Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 6/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.47 |
| ▸ | FNTB | P49356 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997171 | 1.00 | CA2 (0.49) | CA2FNTAPGGT1BFNTBMAPT | |
| Hydrochloric Acid SCHEMBL7993330 | 0.99 | CA2 (0.48) | CA2FNTAPGGT1BFNTBMAPT | |
| Hydrochloric Acid SCHEMBL7993324 | 0.99 | CA2 (0.48) | CA2FNTAPGGT1BFNTBMAPT | |
| SCHEMBL8934740 | 0.95 | MAPT (0.50) | CA2FNTAPGGT1BFNTBMAPT | |
| SCHEMBL8934736 | 0.95 | MAPT (0.50) | CA2FNTAPGGT1BFNTBMAPT | |
| SCHEMBL7996400 | 0.85 | SIRT2 (0.54) | FNTAPGGT1BFNTBLMNA | |
| SCHEMBL7996402 | 0.85 | SIRT2 (0.54) | FNTAPGGT1BFNTBLMNA | |
| Hydrochloric Acid SCHEMBL7996930 | 0.84 | SIRT2 (0.53) | FNTAPGGT1BFNTBLMNA | |
| Hydrochloric Acid SCHEMBL7996929 | 0.84 | SIRT2 (0.53) | FNTAPGGT1BFNTBLMNA | |
| SCHEMBL7994798 | 0.78 | FNTA (0.58) | FNTAPGGT1BFNTBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817629-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2000-03-08 | — | — | EP | claimed |
| EP-0817629-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-14 | — | — | EP | claimed |
| EP-0817629-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0817629-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-14 | — | — | EP | disclosed |
| US-5631280-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1997-05-20 | — | — | US | disclosed |
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |