Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989276 | 0.83 | CYP19A1 (0.51) | CYP19A1PIK3CAPIK3CBPIK3CGADRA2A | |
| SCHEMBL1484854 | 0.81 | FABP6 (0.51) | CYP19A1MAOBNOTUM | |
| SCHEMBL2659588 | 0.78 | CYP19A1 (0.50) | CYP19A1MAOBMAP3K14NPC1RAB9A | |
| SCHEMBL989344 | 0.77 | CYP19A1 (0.47) | CYP19A1MAOB | |
| SCHEMBL6204548 | 0.77 | NPC1 (0.47) | NPC1RAB9APIK3CAPIK3CBPIK3CG | |
| SCHEMBL6208319 | 0.76 | CYP1A2 (0.56) | NPC1RAB9ANPSR1 | |
| SCHEMBL989401 | 0.74 | LMNA (0.43) | CYP19A1MAOBADRA2A | |
| SCHEMBL4879254 | 0.74 | NPC1 (0.45) | CYP19A1MAOBMAP3K14NPC1RAB9A | |
| SCHEMBL31152479 | 0.72 | F7 (0.47) | NOTUM | |
| SCHEMBL9179784 | 0.72 | F7 (0.47) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064675-A1 | CONDENSED THIAZOLAMINES AND THEIR USE AS NEUROPEPTIDE Y5 ANTAGONISTS | NOVARTIS AG (CH) | 2001-09-07 | — | — | WO | disclosed |