Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755709 | 0.98 | HDAC6 (0.39) | HDAC6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7612117 | 0.96 | HDAC6 (0.38) | HDAC6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Bromide SCHEMBL4678013 | 0.96 | HDAC6 (0.38) | HDAC6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Fluoride SCHEMBL124319 | 0.94 | HDAC6 (0.37) | HDAC6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1002067 | 0.93 | HDAC6 (0.39) | HDAC6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31303612 | 0.91 | HDAC6 (0.38) | HDAC6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31314886 | 0.91 | HDAC6 (0.38) | HDAC6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31314895 | 0.91 | HDAC6 (0.38) | HDAC6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3500721 | 0.85 | HDAC6 (0.38) | HDAC6NPC1RAB9ASMN1; SMN2CNR1 | |
| SCHEMBL4379434 | 0.85 | HDAC6 (0.38) | HDAC6NPC1RAB9ASMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060213-A | FOR USE IN THE PROCESS FOR THE PRODUCTION OF LITHOGRAPHIC PRINTING PLATES AND SEMICONDUCTORS SUCH AS INTEGRATED CIRCUITS OR CIRCUIT BOARDS FOR LIQUID CRYSTAL, THERMAL HEAD, ETC. OR OTHER PHOTOFABRICATION PROCESSES | FUJI PHOTO FILM CO., LTD. (KR) | 2000-05-09 | — | — | US | disclosed |