Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.68 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996981 | 1.00 | ALOX15 (0.68) | ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL29414126 | 0.95 | ALOX15 (0.75) | ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL627857 | 0.95 | ALOX15 (0.75) | ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL824520 | 0.86 | ALOX15 (0.67) | ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL29395805 | 0.86 | ALOX15 (0.67) | ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL27515308 | 0.84 | ALOX15 (0.64) | ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL23542362 | 0.83 | ALOX15 (0.62) | ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL29872633 | 0.83 | ALOX15 (0.70) | ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL395984 | 0.83 | ALOX15 (0.70) | ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL38604 | 0.83 | ALOX15 (1.00) | ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025225-A2 | ADDUCTS OF GLYCIDYLESTERS OF ALPHA, ALPHA-BRANCHED CARBOXYLIC ACIDS AND ACRYLIC ACIDS AND POLY(ORTHO ESTER) AS INTERMEDIATE FOR THEIR PREPARATION | RESOLUTION RESEARCH NEDERLAND B.V. (NL) | 2001-04-12 | — | — | WO | disclosed |