Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997322 | 0.93 | KMT2A (0.58) | KMT2AMEN1L3MBTL1MAPTATM | |
| SCHEMBL7851025 | 0.87 | SMN1; SMN2 (0.51) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL23058500 | 0.85 | KMT2A (0.51) | KMT2AMEN1L3MBTL1MAPTATM | |
| SCHEMBL3151234 | 0.85 | ACP3 (0.50) | KMT2AMEN1MAPTCYP2C19SIGMAR1 | |
| SCHEMBL8898408 | 0.81 | KMT2A (0.51) | KMT2AMEN1L3MBTL1CYP2C19SIGMAR1 | |
| SCHEMBL914510 | 0.81 | MAPT (0.67) | KMT2AMEN1L3MBTL1MAPTATM | |
| SCHEMBL106076 | 0.81 | MAPT (0.67) | KMT2AMEN1L3MBTL1MAPTATM | |
| SCHEMBL106075 | 0.81 | MAPT (0.67) | KMT2AMEN1L3MBTL1MAPTATM | |
| SCHEMBL11538164 | 0.79 | KMT2A (0.46) | KMT2AMEN1L3MBTL1MAPTATM | |
| Hydrochloric Acid SCHEMBL1604707 | 0.79 | MAPT (0.65) | KMT2AMEN1L3MBTL1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014335-A1 | PROCESS FOR PREPARATION OF PAROXETIN INTERMEDIATE | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | disclosed |