Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29770337 | 0.69 | AR (0.32) | AR | |
| SCHEMBL15381374 | 0.69 | PARP1 (0.39) | ARALDH1A1LMNA | |
| SCHEMBL3469735 | 0.66 | PSMB8 (0.40) | AR | |
| SCHEMBL10284439 | 0.66 | GAA (0.42) | AR | |
| SCHEMBL11874941 | 0.65 | AR (0.35) | AR | |
| SCHEMBL21225422 | 0.63 | EIF4A3 (0.54) | ALDH1A1LMNA | |
| Urea SCHEMBL28213662 | 0.60 | HTT (0.40) | ALDH1A1CES2CES1 | |
| SCHEMBL31715979 | 0.59 | PRKAG1 (0.43) | EGLN1LMNA | |
| Bicarbonate SCHEMBL16932539 | 0.59 | CA1 (0.52) | LMNACES2CES1 | |
| Bicarbonate SCHEMBL28819166 | 0.59 | CA1 (0.52) | LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001083457-A2 | BENZIMIDAZOLE-2-CARBAMATES AND THEIR USE IN CANCER TREATMENT | THE PROCTER & GAMBLE COMPANY (US) | 2001-11-08 | — | — | WO | disclosed |