Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001283 | 0.93 | NR1H4 (0.43) | MAPTCNR2MEN1KMT2A | |
| SCHEMBL7998796 | 0.93 | NR1H4 (0.43) | MAPTCNR2MEN1KMT2A | |
| SCHEMBL7988886 | 0.91 | MEN1 (0.41) | MAPTCNR2MEN1KMT2A | |
| SCHEMBL7998875 | 0.91 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL8074612 | 0.91 | MAPT (0.48) | MAPTCNR2MEN1KMT2A | |
| SCHEMBL7988890 | 0.90 | MEN1 (0.40) | MAPTCNR2MEN1KMT2A | |
| SCHEMBL8004114 | 0.87 | DHFR (0.41) | MEN1KMT2A | |
| SCHEMBL8004109 | 0.87 | DHFR (0.41) | MEN1KMT2A | |
| SCHEMBL8004926 | 0.86 | MEN1 (0.37) | MAPTCNR2MEN1KMT2ACNR1 | |
| SCHEMBL8004919 | 0.86 | MEN1 (0.37) | MAPTCNR2MEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |