Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998916 | 0.88 | KDM4E (0.37) | TTRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL8003956 | 0.88 | TTR (0.42) | TTRBRPF1KDM4EMAPTALDH1A1 | |
| SCHEMBL8000769 | 0.87 | RORA (0.35) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7997828 | 0.86 | KDM4E (0.45) | TTRBRPF1KDM4EMAPTALDH1A1 | |
| SCHEMBL7988525 | 0.86 | KDM4E (0.45) | TTRBRPF1KDM4EMAPTALDH1A1 | |
| SCHEMBL7999661 | 0.86 | TTR (0.40) | TTRBRPF1KDM4EMAPTALDH1A1 | |
| SCHEMBL7997800 | 0.85 | KDM4E (0.37) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7999048 | 0.85 | KDM4E (0.37) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7998310 | 0.84 | TTR (0.47) | TTRBRPF1KDM4EMAPTALDH1A1 | |
| SCHEMBL7988874 | 0.84 | TTR (0.39) | TTRBRPF1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |