⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14305831 | 1.00 | — | — | |
| SCHEMBL1641546 | 1.00 | — | — | |
| SCHEMBL277326 | 0.84 | TSHR (0.53) | — | |
| SCHEMBL18177926 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL12311768 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL18177927 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL7717560 | 0.74 | — | — | |
| SCHEMBL12115727 | 0.69 | — | — | |
| SCHEMBL9644302 | 0.69 | — | — | |
| SCHEMBL6833025 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230314943-A1 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND METHOD FOR MANUFACTURING RESIST FILM USING THE SAME | MERCK PATENT GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| US-11697639-B2 | Quaternary ammonium salt compound, preparation method therefor and use thereof | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2023-07-11 | — | — | US | disclosed |
| US-10035788-B2 | Maleate salts of (E)-N-{4[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof | WYETH LLC (US) | 2018-07-31 | — | — | US | disclosed |
| US-20180127412-A1 | MALEATE SALTS OF A B-RAF KINASE INHIBITOR, CRYSTALLINE FORMS, METHODS OF PREPARATION, AND USES THEREFORE | BEONE MEDICINES I GMBH (CH) | 2018-05-10 | — | — | US | disclosed |
| US-20180028510-A1 | PREVENTION AND TREATMENT OF THROMBOSIS IN MEDICALLY ILL PATIENTS | ALEXION PHARMACEUTICALS, INC. | 2018-02-01 | — | — | US | disclosed |
| US-20170320852-A1 | MALEATE SALTS OF (E)-N--4-(DIMETHYLAMINO)-2-BUTENAMIDE AND CRYSTALLINE FORMS THEREOF | WYETH LLC | 2017-11-09 | — | — | US | disclosed |
| US-9698204-B2 | Light-emitting substrate, photovoltaic cell, display device, lighting device, electronic device, organic light-emitting diode, and method of manufacturing light-emitting substrate | SHARP KABUSHIKI KAISHA (JP) | 2017-07-04 | — | — | US | disclosed |
| US-9682984-B2 | Methods for the preparation of alcaftadine | CRYSTAL PHARMA S.A.U. (ES) | 2017-06-20 | — | — | US | disclosed |
| US-9630946-B2 | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof | WYETH LLC (US) | 2017-04-25 | — | — | US | disclosed |
| US-9555023-B2 | Pharmaceutical salts and polymorphs of a factor Xa inhibitor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20120238580-A1 | MALEATE SALTS OF 6-(5-CHLORO-2-PYRIDYL)-5-[(4-METHYL-1-PIPERAZINYL)CARBONYLOXY]-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-b]PYRAZINE | SUNOVION PHARMACEUTICALS INC. (US) | 2012-09-20 | — | — | US | disclosed |
| US-8173814-B2 | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof | WYETH LLC (US) | 2012-05-08 | — | — | US | disclosed |
| US-20120095019-A1 | METHODS AND FORMULATIONS OF TREATING THROMBOSIS WITH BETRIXABAN AND A P-GLYCOPROTEIN INHIBITOR | ALEXION PHARMACEUTICALS, INC. | 2012-04-19 | — | — | US | disclosed |
| US-20120071519-A1 | CRYSTALLINE FORMS OF A FACTOR Xa INHIBITOR | ALEXION PHARMACEUTICALS, INC. | 2012-03-22 | — | — | US | disclosed |
| US-20110319627-A1 | METHODS OF SYNTHESIZING FACTOR Xa INHIBITORS | MERCK SHARP & DOHME CORP. | 2011-12-29 | — | — | US | disclosed |
| US-20110229819-A1 | METHOD OF FOIL TRANSFER EMPLOYING FOIL TRANSFERRING FACE FORMING TONER AND IMAGE FORMING METHOD | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2011-09-22 | — | — | US | disclosed |
| US-20110207045-A1 | TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT AND PRODUCTION METHOD THEREOF | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2011-08-25 | — | — | US | disclosed |
| US-20110178393-A1 | Process for the Preparation of Aqueous Solutions of Hyperpolarized Molecules | BRACCO IMAGING S.P.A. (IT) | 2011-07-21 | — | — | US | disclosed |
| US-20110129771-A1 | TRANSPARENT TONER AND IMAGE FORMING METHOD | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2011-06-02 | — | — | US | disclosed |
| US-20110082157-A1 | Piperidinylamino-Thieno [2,3-D] Pyrimidine Compounds | TROVIS PHARMACEUTICALS, LLC | 2011-04-07 | — | — | US | disclosed |