Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MASP2 | O00187 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18177926 | 1.00 | TSHR (0.38) | TSHRTP53EGLN1EGLN3PPARA | |
| SCHEMBL12311768 | 1.00 | TSHR (0.38) | TSHRTP53EGLN1EGLN3PPARA | |
| SCHEMBL14305831 | 0.81 | — | — | |
| SCHEMBL799767 | 0.81 | — | — | |
| SCHEMBL1641546 | 0.81 | — | — | |
| SCHEMBL4109806 | 0.78 | — | — | |
| SCHEMBL351491 | 0.74 | TSHR (0.67) | TSHRTP53EGLN1EGLN3PPARA | |
| SCHEMBL509417 | 0.74 | TSHR (0.67) | TSHRTP53EGLN1EGLN3PPARA | |
| SCHEMBL820982 | 0.74 | TSHR (0.67) | TSHRTP53EGLN1EGLN3PPARA | |
| SCHEMBL2726 | 0.74 | TSHR (0.67) | TSHRTP53EGLN1EGLN3PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160347908-A1 | PROCESS FOR PRODUCING NYLON-6,6 | BASF SE (DE) | 2016-12-01 | — | — | US | disclosed |
| US-20160326092-A1 | METHOD FOR PRODUCING HEXAMETHYLENEDIAMINE | BASF SE (DE) | 2016-11-10 | — | — | US | disclosed |
| US-20160311739-A1 | METHOD FOR PREPARING 1,6-HEXANEDIOL | BASF SE (DE) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326092-A1 | METHOD FOR PRODUCING HEXAMETHYLENEDIAMINE | MUC1, HEXD, HEXA | TSHR 3756/4885TP53 3709/4885EGLN1 1547/4885 |
| US-20160311739-A1 | METHOD FOR PREPARING 1,6-HEXANEDIOL | MUC1, HEXD, HPD | TSHR 4434/4885TP53 3079/4885EGLN1 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.