Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999015 | 0.93 | TDP1 (0.37) | ALDH1A1 | |
| SCHEMBL7999022 | 0.93 | TDP1 (0.37) | ALDH1A1 | |
| SCHEMBL7997501 | 0.88 | ALDH1A1 (0.34) | ARALDH1A1LMNAACHECYP1B1 | |
| SCHEMBL7999110 | 0.88 | AR (0.34) | ARLMNA | |
| SCHEMBL8002087 | 0.88 | TP53 (0.33) | ARALDH1A1LMNAACHECYP1B1 | |
| SCHEMBL7997246 | 0.87 | AR (0.33) | ARALDH1A1LMNAACHECYP1B1 | |
| SCHEMBL8000732 | 0.87 | AR (0.33) | ARALDH1A1LMNA | |
| SCHEMBL7997493 | 0.86 | MAPT (0.37) | ARALDH1A1LMNAACHECYP1B1 | |
| SCHEMBL7998839 | 0.86 | AR (0.34) | ARALDH1A1LMNA | |
| SCHEMBL7997676 | 0.85 | AR (0.32) | ARLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |