Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459 | 0.89 | — | — | |
| SCHEMBL2094168 | 0.89 | LMNA (1.00) | LMNATHRB | |
| SCHEMBL10934241 | 0.88 | — | — | |
| SCHEMBL9518993 | 0.86 | — | — | |
| Ammonia Solution, Strong SCHEMBL15232243 | 0.86 | LMNA (0.92) | LMNATHRB | |
| SCHEMBL2354348 | 0.86 | — | — | |
| SCHEMBL10435620 | 0.86 | — | — | |
| SCHEMBL11207256 | 0.86 | — | — | |
| SCHEMBL3453066 | 0.86 | — | — | |
| SCHEMBL5105333 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015626-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES FOR PYRONIN ANTIBACTERIALS | ANADYS PHARMACEUTICALS, INC. (US) | 2000-03-23 | — | — | WO | disclosed |