Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 18/20 | 0.61 |
| ▸ | HTR2A | P28223 | 15/20 | 0.60 |
| ▸ | HTR2B | P41595 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998314 | 0.92 | HTR2C (0.53) | HTR2CHTR2AHTR2B | |
| SCHEMBL23927854 | 0.82 | HTR2C (0.42) | HTR2CHTR2AHTR2B | |
| SCHEMBL29780344 | 0.82 | HTR2C (0.42) | HTR2CHTR2AHTR2B | |
| SCHEMBL23927852 | 0.82 | HTR2C (0.42) | HTR2CHTR2AHTR2B | |
| SCHEMBL18247631 | 0.79 | CYP19A1 (0.43) | HTR2CHTR2A | |
| SCHEMBL7983996 | 0.78 | HTR2C (0.63) | HTR2CHTR2AHTR2B | |
| SCHEMBL7808564 | 0.78 | CNR2 (0.39) | HTR2CHTR2A | |
| SCHEMBL23927911 | 0.76 | HTR2C (0.54) | HTR2CHTR2A | |
| SCHEMBL15112345 | 0.74 | CNR2 (0.56) | — | |
| SCHEMBL28375979 | 0.74 | KCNA3 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | claimed |