Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 15/20 | 0.53 |
| ▸ | HTR2A | P28223 | 12/20 | 0.52 |
| ▸ | HTR2B | P41595 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997702 | 0.92 | HTR2C (0.61) | HTR2CHTR2AHTR2B | |
| SCHEMBL7983996 | 0.89 | HTR2C (0.63) | HTR2CHTR2AHTR2B | |
| SCHEMBL7998316 | 0.79 | HTR2C (0.42) | HTR2CHTR2AHTR2BMAPT | |
| SCHEMBL23927854 | 0.76 | HTR2C (0.42) | HTR2CHTR2AHTR2BALDH1A1LMNA | |
| SCHEMBL29780344 | 0.76 | HTR2C (0.42) | HTR2CHTR2AHTR2BALDH1A1LMNA | |
| SCHEMBL23927852 | 0.76 | HTR2C (0.42) | HTR2CHTR2AHTR2BALDH1A1LMNA | |
| SCHEMBL18247631 | 0.73 | CYP19A1 (0.43) | HTR2CHTR2AKDM4EALDH1A1MAPT | |
| SCHEMBL7808564 | 0.72 | CNR2 (0.39) | HTR2CHTR2AKDM4EMAPK1 | |
| SCHEMBL23927911 | 0.70 | HTR2C (0.54) | HTR2CHTR2AKDM4EALDH1A1HPGD | |
| SCHEMBL15112345 | 0.68 | CNR2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |