Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996230 | 0.89 | CYP11B1 (0.50) | CYP11B1CYP11B2DRD2DRD3DRD4 | |
| SCHEMBL7998199 | 0.87 | CYP11B1 (0.48) | CYP11B1CYP11B2DRD2DRD3DRD4 | |
| SCHEMBL7996137 | 0.81 | CYP11B1 (0.54) | CYP11B1CYP11B2TNFMEN1KMT2A | |
| SCHEMBL7997671 | 0.79 | CYP11B1 (0.52) | CYP11B1CYP11B2TNFMEN1KMT2A | |
| SCHEMBL7994643 | 0.78 | CYP11B1 (0.56) | CYP11B1CYP11B2TNFMEN1KMT2A | |
| SCHEMBL7996157 | 0.77 | CYP11B1 (0.52) | CYP11B1CYP11B2TNFMEN1KMT2A | |
| SCHEMBL7983622 | 0.75 | CYP11B1 (0.49) | CYP11B1CYP11B2TNFMEN1KMT2A | |
| SCHEMBL7996260 | 0.74 | CYP11B1 (0.48) | CYP11B1CYP11B2TNFMEN1KMT2A | |
| SCHEMBL8418073 | 0.73 | DRD2 (0.70) | DRD2DRD3DRD4ALDH1A1LMNA | |
| SCHEMBL7997859 | 0.73 | CYP11B1 (0.45) | CYP11B1CYP11B2TNFMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |