Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | MATK | P42679 | 1/20 | 0.49 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997857 | 1.00 | KCNH2 (0.61) | KCNH2HRH3DYRK1APIM3RPS6KB1 | |
| SCHEMBL8110519 | 0.90 | KCNH2 (0.73) | KCNH2HRH3DYRK1APIM3RPS6KB1 | |
| SCHEMBL7997798 | 0.86 | KCNH2 (0.45) | KCNH2HRH3DYRK1APIM3RPS6KB1 | |
| SCHEMBL9086828 | 0.84 | KCNH2 (0.54) | KCNH2HRH3DYRK1APIM3RPS6KB1 | |
| SCHEMBL7997785 | 0.84 | KCNH2 (0.51) | KCNH2HRH3DYRK1APIM3RPS6KB1 | |
| SCHEMBL7997787 | 0.84 | KCNH2 (0.51) | KCNH2HRH3DYRK1APIM3RPS6KB1 | |
| Hydrochloric Acid SCHEMBL8111805 | 0.83 | KCNH2 (0.54) | KCNH2HRH3DYRK1APIM3RPS6KB1 | |
| SCHEMBL9087871 | 0.83 | KCNH2 (0.54) | KCNH2HRH3DYRK1APIM3RPS6KB1 | |
| SCHEMBL7997606 | 0.83 | RPS6KB1 (0.51) | KCNH2HRH3DYRK1APIM3RPS6KB1 | |
| SCHEMBL8010003 | 0.83 | RPS6KB1 (0.51) | KCNH2HRH3DYRK1APIM3RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | claimed |
| EP-0593766-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | claimed |
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| EP-0593766-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |