Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | MATK | P42679 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997785 | 1.00 | KCNH2 (0.51) | KCNH2HRH3CYP3A4RPS6KB1MATK | |
| SCHEMBL8009438 | 0.87 | KCNH2 (0.38) | KCNH2HRH3CYP3A4 | |
| SCHEMBL8007518 | 0.84 | KMT2A (0.43) | KCNH2HRH3CYP3A4RPS6KB1MATK | |
| SCHEMBL7997965 | 0.84 | KMT2A (0.43) | KCNH2HRH3CYP3A4RPS6KB1MATK | |
| SCHEMBL7997794 | 0.84 | KCNH2 (0.61) | KCNH2HRH3CYP3A4RPS6KB1MATK | |
| SCHEMBL7997857 | 0.84 | KCNH2 (0.61) | KCNH2HRH3CYP3A4RPS6KB1MATK | |
| SCHEMBL6183266 | 0.83 | ALDH1A1 (0.50) | CYP3A4ALDH1A1KDM4EPOLBTOP2A | |
| SCHEMBL6183264 | 0.83 | ALDH1A1 (0.50) | CYP3A4ALDH1A1KDM4EPOLBTOP2A | |
| SCHEMBL9403595 | 0.79 | KCNH2 (0.51) | KCNH2HRH3ALDH1A1KDM4EPOLB | |
| SCHEMBL8132608 | 0.79 | KCNH2 (0.49) | KCNH2HRH3ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | claimed |
| EP-0593766-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | claimed |
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| EP-0593766-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |