Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997804 | 1.00 | EGFR (0.47) | EGFRL3MBTL1MCHR1DHFRSAE1 | |
| SCHEMBL8001387 | 0.99 | L3MBTL1 (0.46) | EGFRL3MBTL1MCHR1DHFRSAE1 | |
| SCHEMBL8001392 | 0.99 | L3MBTL1 (0.46) | EGFRL3MBTL1MCHR1DHFRSAE1 | |
| SCHEMBL7988830 | 0.94 | EGFR (0.43) | EGFRL3MBTL1MCHR1DHFRSAE1 | |
| SCHEMBL7988827 | 0.94 | EGFR (0.43) | EGFRL3MBTL1MCHR1DHFRSAE1 | |
| SCHEMBL8001827 | 0.94 | L3MBTL1 (0.42) | EGFRL3MBTL1MCHR1DHFRSAE1 | |
| SCHEMBL8001824 | 0.94 | L3MBTL1 (0.42) | EGFRL3MBTL1MCHR1DHFRSAE1 | |
| SCHEMBL7988117 | 0.93 | L3MBTL1 (0.43) | EGFRL3MBTL1MCHR1DHFRSAE1 | |
| SCHEMBL7988120 | 0.93 | L3MBTL1 (0.43) | EGFRL3MBTL1MCHR1DHFRSAE1 | |
| SCHEMBL7988389 | 0.93 | L3MBTL1 (0.41) | EGFRL3MBTL1MCHR1DHFRSAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |