Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.36 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.36 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.36 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.36 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.36 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.36 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.36 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.36 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.36 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.36 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001904 | 1.00 | EGFR (0.38) | EGFRMCHR1DHFRPTGESL3MBTL1 | |
| SCHEMBL8001910 | 1.00 | EGFR (0.38) | EGFRMCHR1DHFRPTGESL3MBTL1 | |
| SCHEMBL8001020 | 0.99 | EGFR (0.38) | EGFRMCHR1DHFRPTGESL3MBTL1 | |
| SCHEMBL8001022 | 0.99 | EGFR (0.38) | EGFRMCHR1DHFRPTGESL3MBTL1 | |
| SCHEMBL8001017 | 0.99 | EGFR (0.38) | EGFRMCHR1DHFRPTGESL3MBTL1 | |
| SCHEMBL8004365 | 0.97 | L3MBTL1 (0.38) | EGFRMCHR1DHFRPTGESL3MBTL1 | |
| SCHEMBL7997981 | 0.97 | EGFR (0.39) | EGFRMCHR1DHFRPTGESL3MBTL1 | |
| SCHEMBL8002013 | 0.97 | L3MBTL1 (0.38) | EGFRMCHR1DHFRPTGESL3MBTL1 | |
| SCHEMBL8004369 | 0.97 | L3MBTL1 (0.38) | EGFRMCHR1DHFRPTGESL3MBTL1 | |
| SCHEMBL8002009 | 0.97 | L3MBTL1 (0.38) | EGFRMCHR1DHFRPTGESL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |