⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167764 | 0.81 | PTGS1 (0.43) | — | |
| SCHEMBL14578111 | 0.79 | — | — | |
| SCHEMBL2889658 | 0.79 | PTGS1 (0.41) | — | |
| SCHEMBL226337 | 0.79 | PTGS1 (0.41) | — | |
| SCHEMBL7770123 | 0.79 | PTGS1 (0.41) | — | |
| SCHEMBL7904192 | 0.79 | PTGS1 (0.41) | — | |
| SCHEMBL10358209 | 0.78 | PTGS1 (0.45) | — | |
| SCHEMBL27593973 | 0.77 | — | — | |
| SCHEMBL1191477 | 0.73 | — | — | |
| SCHEMBL1070054 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845938-B1 | METHODS AND RELATED COMPOSITIONS FOR REDUCTION OF FAT AND SKIN TIGHTENING | LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) | 2019-04-03 | — | — | EP | claimed |
| US-20250205242-A1 | CDK7 INHIBITORS FOR ANTIVIRAL TREATMENT | LEAD DISCOVERY CENTER GMBH (DE) | 2025-06-26 | — | — | US | disclosed |
| EP-4493193-A1 | CDK7 INHIBITORS FOR ANTIVIRAL TREATMENT | Qurient Co., Ltd. (KR) | 2025-01-22 | — | — | EP | disclosed |
| WO-2023175173-A1 | CDK7 INHIBITORS FOR ANTIVIRAL TREATMENT | QURIENT CO., LTD. (KR) | 2023-09-21 | — | — | WO | disclosed |
| CN-108191940-B | Synthetic bile acid compositions, methods and formulations | 艾尔健销售有限责任公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-101711254-A | Synthetic bile acid compositions, methods and formulations | KYTHERA BIOPHARMACEUTICALS INC | 2010-05-19 | — | — | CN | disclosed |
| US-6287853-B1 | GENETICALLY ENGINEERED ESCHERICHIA PLASMID; MARKING ANTIBIOTIC RESISTANCE; ARTIFICIAL CHROMOSOMES; GENETIC MAPPING | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY | 2001-09-11 | — | — | US | disclosed |
| EP-0804222-A4 | ACCESSORY FACTOR FUNCTION FOR INTERFERON GAMMA AND ITS RECEPTOR | UNIV NEW JERSEY MED (US) | 1998-08-12 | — | — | EP | disclosed |
| EP-0804222-A1 | ACCESSORY FACTOR FUNCTION FOR INTERFERON GAMMA AND ITS RECEPTOR | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996001276-A1 | EXPRESSION OF A FUNCTIONAL HUMAN TYPE I INTERFERON RECEPTOR | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) | 1996-01-18 | — | — | WO | disclosed |
| WO-1995005847-A1 | ACCESSORY FACTOR FUNCTION FOR INTERFERON GAMMA AND ITS RECEPTOR | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) | 1995-03-02 | — | — | WO | disclosed |