Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30358382 | 0.88 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL11934536 | 0.84 | GAA (0.52) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL2795084 | 0.83 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL22042909 | 0.83 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL30612629 | 0.83 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL7978062 | 0.81 | CA12 (0.48) | ACLYALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7984144 | 0.79 | KDM4E (0.47) | ACLYALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL21815291 | 0.79 | MEN1 (0.65) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL23176649 | 0.79 | KDM4E (0.53) | ACLYALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL7997880 | 0.78 | ESR1 (0.50) | ACLYSMN1; SMN2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |