SCHEMBL7998191

SCHEMBL7998191

CCCCCCCCNc1ccc2c(OCC=C(C)C)c(OCCCCCCCC)c(=O)n(C)c2c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 2/20 0.33
TERT O14746 1/20 0.33
ALDH1A1 P00352 4/20 0.33
LMNA P02545 1/20 0.33
ACHE P22303 1/20 0.33
CYP1B1 Q16678 1/20 0.33
GSK3B P49841 2/20 0.33
ADRA2A P08913 1/20 0.32
KDM4E B2RXH2 3/20 0.32
HPGD P15428 2/20 0.32
HSD17B10 Q99714 1/20 0.32
CNR2 P34972 2/20 0.32
TP53 P04637 1/20 0.32
GAA P10253 2/20 0.31
MAPT P10636 1/20 0.31
AR P10275 1/20 0.31
ATM Q13315 1/20 0.31
GLA P06280 1/20 0.31
RXRA P19793 1/20 0.31
S1PR2 O95136 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7997246 0.98 AR (0.33) ABL1TERTALDH1A1LMNAACHE
SCHEMBL7997501 0.94 ALDH1A1 (0.34) ALDH1A1LMNAACHECYP1B1KDM4E
SCHEMBL8001527 0.93 ABL1 (0.33) ABL1TERTALDH1A1LMNAACHE
SCHEMBL8004822 0.92 TDP1 (0.39) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL7998713 0.92 TDP1 (0.39) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL7998717 0.92 TDP1 (0.39) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL8004818 0.92 TDP1 (0.39) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL7998040 0.90 TDP1 (0.39) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL7997972 0.90 TDP1 (0.39) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL7997966 0.90 TDP1 (0.39) ALDH1A1KDM4EHPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6291743-B2 Transgenic plants expressing mutant geminivirus AC1 or C1 genes SEMINIS VEGETABLE SEEDS, INC. 2001-09-18 US disclosed
US-6114352-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-09-05 US disclosed
EP-0785190-B1 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK & CHEMICALS (JP) 2000-08-16 EP disclosed
US-5942521-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-08-24 US disclosed