⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37346 | 1.00 | — | — | |
| SCHEMBL4625383 | 1.00 | — | — | |
| SCHEMBL714330 | 0.76 | — | — | |
| SCHEMBL87537 | 0.76 | — | — | |
| SCHEMBL3504356 | 0.76 | — | — | |
| SCHEMBL8741368 | 0.76 | — | — | |
| SCHEMBL703453 | 0.76 | — | — | |
| SCHEMBL12115727 | 0.76 | — | — | |
| SCHEMBL20662894 | 0.76 | ALDH1A1 (0.48) | — | |
| SCHEMBL17225201 | 0.76 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021163679-A1 | METHODS FOR RAPID SYNTHESIS OF PYRANOANTHOCYANINS | OHIO STATE INNOVATION FOUNDATION (US) | 2021-08-19 | — | — | WO | disclosed |
| US-20170326119-A1 | NOVEL PHARMACEUTICAL SALTS AND POLYMORPHS OF A FACTOR XA INHIBITOR | MILLENNIUM PHARMACEUTICALS, INC. | 2017-11-16 | — | — | US | disclosed |
| US-9555023-B2 | Pharmaceutical salts and polymorphs of a factor Xa inhibitor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-9505774-B2 | Polymorphic forms of icotinib maleate and uses thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2016-11-29 | — | — | US | disclosed |
| US-20160137658-A1 | POLYMORPHIC FORMS OF ICOTINIB MALEATE AND USES THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2016-05-19 | — | — | US | disclosed |
| US-20160101089-A1 | NOVEL PHARMACEUTICAL SALTS AND POLYMORPHS OF A FACTOR XA INHIBITOR | MILLENNIUM PHARMACEUTICALS, INC. | 2016-04-14 | — | — | US | disclosed |
| US-9221758-B2 | Methods of synthesizing pharmaceutical salts of a factor Xa inhibitor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150203501-A1 | MALEATE SALTS OF 6-(5-CHLORO-2-PYRIDYL)-5-[(4-METHYL-1-PIPERAZINYL)CARBONYLOXY]-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-b]PYRAZINE | SUNOVION PHARMACEUTICALS INC. | 2015-07-23 | — | — | US | disclosed |
| US-9061019-B2 | Pharmaceutical salts and polymorphs of a factor Xa inhibitor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-8987463-B2 | Methods of synthesizing factor Xa inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-03-24 | — | — | US | disclosed |
| US-8394964-B2 | Methods of synthesizing factor Xa inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120238580-A1 | MALEATE SALTS OF 6-(5-CHLORO-2-PYRIDYL)-5-[(4-METHYL-1-PIPERAZINYL)CARBONYLOXY]-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-b]PYRAZINE | SUNOVION PHARMACEUTICALS INC. (US) | 2012-09-20 | — | — | US | disclosed |
| US-8232294-B2 | Amino ester derivatives, sailts thereof and methods of use | Xi, Ning (US) | 2012-07-31 | — | — | US | disclosed |
| US-20120071519-A1 | CRYSTALLINE FORMS OF A FACTOR Xa INHIBITOR | ALEXION PHARMACEUTICALS, INC. | 2012-03-22 | — | — | US | disclosed |
| US-20120046230-A1 | Combination Anticoagulant Therapy With A Compound That Acts As A Factor Xa Inhibitor | MILLENNIUM PHARMACEUTICALS, INC. | 2012-02-23 | — | — | US | disclosed |
| US-20110319627-A1 | METHODS OF SYNTHESIZING FACTOR Xa INHIBITORS | MERCK SHARP & DOHME CORP. | 2011-12-29 | — | — | US | disclosed |
| US-7985502-B2 | Containing formic ester additive; cycling properties, electrical capacity, storage during charging | UBE INDUSTRIES, LTD. (JP) | 2011-07-26 | — | — | US | disclosed |
| US-20110033459-A1 | COMBINATION THERAPY WITH A COMPOUND ACTING AS A PLATELET ADP RECEPTOR INHIBITOR | PORTOLA PHARMACEUTICALS, INC. | 2011-02-10 | — | — | US | disclosed |
| US-20080241704-A1 | Nonaqueous Electrolyte Solution and Lithium Secondary Battery Using Same | UBE INDUSTRIES, LTD (JP) | 2008-10-02 | — | — | US | disclosed |
| EP-1729365-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME | Ube Industries, Ltd. (JP) | 2006-12-06 | — | — | EP | disclosed |