Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10584305 | 1.00 | LMNA (0.49) | LMNAAKR1B10AKR1B1NPC1L3MBTL1 | |
| SCHEMBL28613781 | 0.89 | LMNA (0.50) | LMNAAKR1B10AKR1B1NPC1L3MBTL1 | |
| SCHEMBL27890646 | 0.89 | LMNA (0.50) | LMNAAKR1B10AKR1B1NPC1L3MBTL1 | |
| SCHEMBL28033458 | 0.83 | LMNA (0.53) | LMNAAKR1B10AKR1B1NPC1L3MBTL1 | |
| SCHEMBL13784835 | 0.82 | GLA (0.53) | LMNAAKR1B10AKR1B1NPC1L3MBTL1 | |
| SCHEMBL869265 | 0.82 | MAPT (0.64) | LMNAAKR1B10AKR1B1NPC1GLA | |
| SCHEMBL869266 | 0.82 | MAPT (0.64) | LMNAAKR1B10AKR1B1NPC1GLA | |
| SCHEMBL2357380 | 0.78 | MEN1 (0.42) | LMNANPC1L3MBTL1GLATDP1 | |
| Alcohol SCHEMBL8953241 | 0.78 | LMNA (0.51) | LMNAAKR1B10AKR1B1NPC1L3MBTL1 | |
| Ethylene SCHEMBL28572934 | 0.78 | LMNA (0.51) | LMNAAKR1B10AKR1B1NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083575-A | MULTILAYER ELEMENT WITH POLYMER | FUJI XEROX CO., LTD. (JP) | 2000-07-04 | — | — | US | claimed |
| CN-108478798-B | Preparation method of micro-hydrogel capable of loading and slowly releasing hydrophilic and hydrophobic drugs simultaneously | 浙江大学 | 2020-02-14 | — | — | CN | disclosed |
| US-6083575-A | MULTILAYER ELEMENT WITH POLYMER | FUJI XEROX CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0306784-A2 | Presensitized lithographic printing plate for dry lithography, and process for its production | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-15 | — | — | EP | disclosed |