Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10160138 | 0.88 | EPHX2 (0.69) | EPHX2KMT2AMEN1HDAC1HDAC3 | |
| SCHEMBL7097847 | 0.83 | EPHX2 (0.76) | EPHX2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1073026 | 0.81 | KMT2A (0.57) | EPHX2KMT2AMEN1HDAC1HDAC3 | |
| SCHEMBL10797671 | 0.81 | CA1 (0.57) | EPHX2KMT2AMEN1ALDH1A1GLS | |
| SCHEMBL11627580 | 0.80 | GAA (0.60) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL28543839 | 0.79 | EPHX2 (0.46) | EPHX2KMT2AMEN1HDAC1HDAC3 | |
| SCHEMBL3454266 | 0.79 | EPHX2 (0.69) | EPHX2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL13544615 | 0.79 | EPHX2 (0.69) | EPHX2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11628339 | 0.79 | NLRP3 (0.61) | NPC1RAB9AKMT2AMEN1HDAC1 | |
| SCHEMBL22196106 | 0.78 | KMT2A (0.78) | EPHX2NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074771-A1 | PYRROLE-2,5-DIONE DERIVATIVES FOR THE TREATMENT OF DIABETES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-10-11 | — | — | WO | disclosed |