Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.43 |
| ▸ | HMGCR | P04035 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28783031 | 1.00 | PTPN7 (0.43) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL5168905 | 1.00 | PTPN7 (0.43) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL7998451 | 1.00 | PTPN7 (0.43) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL5169819 | 1.00 | PTPN7 (0.43) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL5169816 | 1.00 | PTPN7 (0.43) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL10632895 | 1.00 | PTPN7 (0.43) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL7987835 | 1.00 | PTPN7 (0.43) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL5170452 | 1.00 | PTPN7 (0.43) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL5168889 | 1.00 | PTPN7 (0.43) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL5170466 | 1.00 | PTPN7 (0.43) | PTPN7HMGCRTSHRTHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10731159-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-08-04 | — | — | US | disclosed |
| US-20200080086-A1 | CATIONIC LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-03-12 | — | — | US | disclosed |
| EP-3020701-B1 | NOVEL LIPID | DAIICHI SANKYO CO LTD (JP) | 2018-09-26 | — | — | EP | disclosed |
| US-20180051285-A1 | CATIONIC LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-02-22 | — | — | US | disclosed |
| US-9803199-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-10-31 | — | — | US | disclosed |
| US-20160257951-A1 | NOVEL LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-08 | — | — | US | disclosed |
| EP-3020701-A1 | NOVEL LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-6288038-B1 | ACCELERATE APOLIPOPROTEIN E PRODUCTION; NERVOUS SYSTEM DISORDERS, ALZHEIMER*S DISEASE; ANTILIPEMIC AGENTS | NISSHIN SEIFUN GROUP INC. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-1028126-A1 | DEPSIPEPTIDE DERIVATIVES BEARING PIPERAZINONE RINGS | Nisshin Flour Milling Co., Ltd. (JP) | 2000-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257951-A1 | NOVEL LIPID | NPC1L1, CETP, LIPC | PTPN7 3976/4885HMGCR 292/4885TSHR 4094/4885 |
| US-20180051285-A1 | CATIONIC LIPID | CETP, NPC1L1, LIPA | PTPN7 3962/4885HMGCR 511/4885TSHR 3456/4885 |
| US-20200080086-A1 | CATIONIC LIPID | CETP, NPC1L1, LIPA | PTPN7 3962/4885HMGCR 511/4885TSHR 3456/4885 |
| US-10731159-B2 | Cationic lipid | CETP, NPC1L1, LIPA | PTPN7 3962/4885HMGCR 511/4885TSHR 3456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.