Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000682 | 0.96 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EGAAGFER | |
| SCHEMBL7997220 | 0.92 | MEN1 (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7997665 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EGAAGFER | |
| SCHEMBL7997102 | 0.90 | PSEN1 (0.42) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7998014 | 0.90 | PSEN1 (0.42) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7997266 | 0.88 | MEN1 (0.41) | ALDH1A1MAPTKDM4EGAAMEN1 | |
| SCHEMBL8004254 | 0.88 | MEN1 (0.41) | ALDH1A1MAPTKDM4EGAAMEN1 | |
| SCHEMBL8004676 | 0.88 | MEN1 (0.39) | ALDH1A1MAPTKDM4EGAAMEN1 | |
| SCHEMBL8001776 | 0.87 | TTR (0.39) | ALDH1A1MAPTKDM4EGAAGFER | |
| SCHEMBL8004073 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |