SCHEMBL7998614

SCHEMBL7998614

C1CCN(CCN2CCNC2)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 4/20 0.48
HRH3 Q9Y5N1 3/20 0.44
RAD52 P43351 1/20 0.41
POLB P06746 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CARM1 Q86X55 1/20 0.34
PRMT6 Q96LA8 1/20 0.34
PRMT8 Q9NR22 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
MAPK1 P28482 1/20 0.34
MEN1 O00255 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
ADRA2C P18825 1/20 0.34
CCR2 P41597 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15834899 0.98 CXCR4 (0.50) CXCR4HRH3RAD52POLBSMN1; SMN2
SCHEMBL28078047 0.87 CXCR4 (0.60) CXCR4HRH3RAD52POLBSMN1; SMN2
SCHEMBL6913246 0.87 CXCR4 (0.60) CXCR4HRH3RAD52POLBSMN1; SMN2
SCHEMBL1914465 0.87 CXCR4 (0.60) CXCR4HRH3RAD52POLBSMN1; SMN2
SCHEMBL946201 0.85 CXCR4 (0.62) CXCR4HRH3RAD52POLBSMN1; SMN2
SCHEMBL13661067 0.83 CXCR4 (0.68) CXCR4HRH3RAD52POLBSMN1; SMN2
SCHEMBL21480703 0.82 CXCR4 (0.48) CXCR4HRH3POLBSMN1; SMN2MEN1
SCHEMBL12992865 0.79 CXCR4 (0.62) CXCR4HRH3RAD52POLBSMN1; SMN2
SCHEMBL29788395 0.79 SMN1; SMN2 (0.45) CXCR4HRH3POLBSMN1; SMN2ALDH1A1
SCHEMBL6644934 0.78 CXCR4 (0.72) CXCR4HRH3RAD52POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6294541-B1 ENZYME INHIBITORS USING PURINE COMPOUNDS AS ANTIHISTAMINES EURO-CELTIQUE S.A. (LU) 2001-09-25 US disclosed