Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 2/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20880133 | 0.80 | KDM4E (0.61) | CDK1KDM4ETMIGD3ADORA2AADORA1 | |
| SCHEMBL21121655 | 0.75 | SMN1; SMN2 (0.55) | CDK1KDM4ETMIGD3ADORA2AADORA1 | |
| SCHEMBL4382069 | 0.74 | CDK1 (1.00) | CDK1KDM4ETMIGD3ADORA2AADORA1 | |
| SCHEMBL8011473 | 0.74 | CDK1 (0.63) | CDK1KDM4ETMIGD3ADORA2AADORA1 | |
| SCHEMBL1387903 | 0.72 | ALDH1A1 (0.43) | CDK1TMIGD3ADORA2AADORA1HTT | |
| SCHEMBL7382606 | 0.72 | TMIGD3 (0.49) | KDM4ETMIGD3ADORA2AADORA1EGFR | |
| SCHEMBL9567831 | 0.70 | AURKA (0.40) | CDK1KDM4EHTTCCNB2CCNB1 | |
| SCHEMBL24667246 | 0.69 | CDK1 (0.63) | CDK1KDM4ETMIGD3ADORA2AADORA1 | |
| SCHEMBL1388236 | 0.69 | PDE4A (0.52) | ADORA2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28829351 | 0.69 | FLT1 (0.60) | CDK1KDM4ECCNB2CCNB1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033657-A1 | METHOD TO IDENTIFY REGULATORS OF CDK ACTIVITY | CROPDESIGN N.V. (BE) | 2000-06-15 | — | — | WO | claimed |
| WO-2000033657-A1 | METHOD TO IDENTIFY REGULATORS OF CDK ACTIVITY | CROPDESIGN N.V. (BE) | 2000-06-15 | — | — | WO | disclosed |