Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27557539 | 0.80 | ALDH1A1 (0.50) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL7459283 | 0.80 | ATM (0.47) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL10582914 | 0.78 | ATM (0.40) | ATMHCAR2HPGDTSHRALDH1A1 | |
| SCHEMBL16866042 | 0.78 | ATM (0.70) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL13729941 | 0.78 | ATM (0.70) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL690840 | 0.77 | ATM (0.76) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL9561881 | 0.77 | ATM (0.76) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL690841 | 0.77 | ATM (0.76) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL28154 | 0.76 | ATM (1.00) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL269917 | 0.76 | ATM (1.00) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776334-A4 | STABLE ANALOGS OF BIOACTIVE PEPTIDES CONTAINING DISULFIDE LINKAGES | MALLINCKRODT MEDICAL INC (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0776334-A1 | STABLE ANALOGS OF BIOACTIVE PEPTIDES CONTAINING DISULFIDE LINKAGES | MALLINCKRODT MEDICAL, INC. (US) | 1997-06-04 | — | — | EP | disclosed |
| WO-1996003429-A1 | STABLE ANALOGS OF BIOACTIVE PEPTIDES CONTAINING DISULFIDE LINKAGES | MALLINCKRODT MEDICAL, INC. (US) | 1996-02-08 | — | — | WO | disclosed |