Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 10/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 10/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 10/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 10/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 10/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.50 |
| ▸ | HTR3B | O95264 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387687 | 0.97 | KCNA3 (0.59) | ALDH1A1KCNA3PSEN1PSEN2APH1B | |
| SCHEMBL11377528 | 0.95 | ALDH1A1 (0.61) | ALDH1A1KCNA3PSEN1PSEN2APH1B | |
| SCHEMBL11379340 | 0.95 | ALDH1A1 (0.64) | ALDH1A1KCNA3PSEN1PSEN2APH1B | |
| SCHEMBL11389778 | 0.93 | ALDH1A1 (0.63) | ALDH1A1KCNA3PSEN1PSEN2APH1B | |
| SCHEMBL11389203 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KCNA3MAPTPKMLMNA | |
| SCHEMBL25493370 | 0.84 | KCNA3 (0.78) | ALDH1A1KCNA3MAPTLMNAHPGD | |
| SCHEMBL11385072 | 0.84 | KCNA3 (0.78) | ALDH1A1KCNA3MAPTLMNAHPGD | |
| SCHEMBL11377058 | 0.84 | KCNA3 (0.78) | ALDH1A1KCNA3MAPTLMNAHPGD | |
| SCHEMBL11394549 | 0.84 | KCNA3 (0.78) | ALDH1A1KCNA3MAPTLMNAHPGD | |
| SCHEMBL8081190 | 0.84 | ALDH1A1 (0.54) | ALDH1A1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |