Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998867 | 0.87 | AR (0.43) | ALDH1A1HPGDSERPINE1KDM4EHSD17B10 | |
| SCHEMBL7997292 | 0.87 | AR (0.43) | ALDH1A1HPGDSERPINE1KDM4EHSD17B10 | |
| SCHEMBL8004780 | 0.82 | AR (0.44) | ALDH1A1HPGDSERPINE1KDM4EHSD17B10 | |
| SCHEMBL7988466 | 0.81 | MAOA (0.53) | MAOAERCC1FEN1ERCC4ALDH1A1 | |
| SCHEMBL8001710 | 0.81 | GSK3B (0.43) | ALDH1A1HPGDKDM4EHSD17B10GSK3B | |
| SCHEMBL7997301 | 0.81 | GSK3B (0.43) | ALDH1A1HPGDKDM4EHSD17B10GSK3B | |
| SCHEMBL7997507 | 0.77 | GPR17 (0.37) | ALDH1A1SERPINE1KDM4EGSK3B | |
| SCHEMBL6579035 | 0.77 | NPC1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10GSK3B | |
| SCHEMBL7992045 | 0.77 | PARP1 (0.48) | SERPINE1 | |
| SCHEMBL7999303 | 0.77 | PARP1 (0.48) | SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |