Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324123 | 0.83 | L3MBTL1 (0.40) | HPGDLMNAL3MBTL1KDM4ETLR9 | |
| SCHEMBL6627247 | 0.78 | PPIA (0.41) | HPGDLMNANR1H2PPIAKDM4E | |
| SCHEMBL5865339 | 0.77 | TLR9 (0.33) | LMNAL3MBTL1PPIAKDM4ESMN1; SMN2 | |
| SCHEMBL5865337 | 0.77 | TLR9 (0.33) | LMNAL3MBTL1PPIAKDM4ESMN1; SMN2 | |
| SCHEMBL8132245 | 0.76 | MRGPRX4 (0.36) | L3MBTL1PPIANPSR1 | |
| SCHEMBL12154966 | 0.74 | L3MBTL1 (0.34) | HPGDL3MBTL1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL5864960 | 0.74 | TLR9 (0.33) | L3MBTL1PPIAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL5864958 | 0.74 | TLR9 (0.33) | L3MBTL1PPIAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL6618750 | 0.73 | L3MBTL1 (0.42) | HPGDLMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL19383383 | 0.73 | TLR9 (0.35) | HPGDLMNAL3MBTL1KDM4ETLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001083482-A1 | DNA ALKYLATING AGENT AND ACTIVATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2001-11-08 | — | — | WO | disclosed |