Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 20/20 | 0.78 |
| ▸ | PRKCD | Q05655 | 14/20 | 0.78 |
| ▸ | PRKCA | P17252 | 6/20 | 0.78 |
| ▸ | PRKCG | P05129 | 1/20 | 0.78 |
| ▸ | PRKCB | P05771 | 1/20 | 0.78 |
| ▸ | PRKCH | P24723 | 1/20 | 0.78 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.78 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22412741 | 1.00 | PRKCQ (0.78) | PRKCQPRKCDPRKCAPRKCGPRKCB | |
| SCHEMBL16848401 | 1.00 | PRKCQ (0.78) | PRKCQPRKCDPRKCAPRKCGPRKCB | |
| SCHEMBL800481 | 1.00 | PRKCQ (0.78) | PRKCQPRKCDPRKCAPRKCGPRKCB | |
| SCHEMBL778875 | 0.93 | PRKCQ (0.77) | PRKCQPRKCDPRKCAPRKCGPRKCB | |
| SCHEMBL778874 | 0.93 | PRKCQ (0.77) | PRKCQPRKCDPRKCAPRKCGPRKCB | |
| SCHEMBL16863939 | 0.92 | PRKCQ (0.67) | PRKCQPRKCDPRKCAPRKCGPRKCB | |
| SCHEMBL800222 | 0.92 | PRKCQ (0.67) | PRKCQPRKCDPRKCAPRKCGPRKCB | |
| SCHEMBL14725875 | 0.92 | PRKCQ (0.65) | PRKCQPRKCDPRKCAPRKCGPRKCB | |
| SCHEMBL800210 | 0.91 | PRKCQ (0.77) | PRKCQPRKCDPRKCAPRKCGPRKCB | |
| SCHEMBL799932 | 0.91 | PRKCQ (0.66) | PRKCQPRKCDPRKCAPRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024025896-A2 | PROTEIN KINASE C (PKC) THETA INHIBITOR COMPOUNDS | EVOMMUNE, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| EP-3046560-B1 | STEM CELL MODULATION II | EPIAXIS THERAPEUTICS PTY LTD (AU) | 2021-01-06 | — | — | EP | disclosed |
| US-20200289437-A1 | Compositions for Modulating Cancer Stem Cells and Uses Therefor | EpiAxis Therapeutics Pty Ltd. (AU) | 2020-09-17 | — | — | US | disclosed |
| US-20200282010-A1 | IMMUNOGENIC COMPOSITIONS AND USES THEREFOR | EPIAXIS THERAPEUTICS PTY LTD (AU) | 2020-09-10 | — | — | US | disclosed |
| US-20200282010-A1 | IMMUNOGENIC COMPOSITIONS AND USES THEREFOR | EPIAXIS THERAPEUTICS PTY LTD (AU) | 2020-09-10 | — | — | US | disclosed |
| CN-111587120-A | Immunogenic compositions and uses thereof | 艾比克斯治疗私人有限公司 | 2020-08-25 | — | — | CN | disclosed |
| US-10736892-B2 | Stem cell modulation II | EpiAxis Therapeutics Pty Ltd. (AU) | 2020-08-11 | — | — | US | disclosed |
| US-10736892-B2 | Stem cell modulation II | EpiAxis Therapeutics Pty Ltd. (AU) | 2020-08-11 | — | — | US | disclosed |
| US-20190192509-A1 | Stem Cell Modulation II | EpiAxis Therapeutics Pty Ltd. (AU) | 2019-06-27 | — | — | US | disclosed |
| US-20190192509-A1 | Stem Cell Modulation II | EpiAxis Therapeutics Pty Ltd. (AU) | 2019-06-27 | — | — | US | disclosed |
| US-20160354367-A1 | Stem Cell Modulation II | UNIVERSITY OF CANBERRA (AU) | 2016-12-08 | — | — | US | disclosed |
| US-20160354367-A1 | Stem Cell Modulation II | UNIVERSITY OF CANBERRA (AU) | 2016-12-08 | — | — | US | disclosed |
| EP-2528917-B1 | PYRAZOLOPYRIDINES USEFUL FOR THE TREATMENT OF AUTOIMMUNE, INFLAMMATORY OR (HYPER)PROLIFERATIVE DISEASES | VERTEX PHARMA (US) | 2016-10-19 | — | — | EP | disclosed |
| EP-2528917-B1 | PYRAZOLOPYRIDINES USEFUL FOR THE TREATMENT OF AUTOIMMUNE, INFLAMMATORY OR (HYPER)PROLIFERATIVE DISEASES | VERTEX PHARMA (US) | 2016-10-19 | — | — | EP | disclosed |
| US-9067932-B2 | Pyrazolopyridine kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-06-30 | — | — | US | disclosed |
| US-9067932-B2 | Pyrazolopyridine kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-06-30 | — | — | US | disclosed |
| US-9067932-B2 | Pyrazolopyridine kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-06-30 | — | — | US | disclosed |
| US-20120071494-A1 | PYRAZOLOPYRIDINE KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120071494-A1 | PYRAZOLOPYRIDINE KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-03-22 | — | — | US | disclosed |
| WO-2011094273-A1 | PYRAZOLOPYRIDINE KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10736892-B2 | Stem cell modulation II | PRKCQ, PRKCI, PRKCG | PRKCQ 1/4885PRKCD 9/4885PRKCA 6/4885 |
| US-20200282010-A1 | IMMUNOGENIC COMPOSITIONS AND USES THEREFOR | NFATC1, PRKCQ, PRKCH | PRKCQ 2/4885PRKCD 8/4885PRKCA 6/4885 |
| US-20200289437-A1 | Compositions for Modulating Cancer Stem Cells and Uses Therefor | PRKCQ, PRKCG, PRKCH | PRKCQ 1/4885PRKCD 12/4885PRKCA 5/4885 |
| US-20120071494-A1 | PYRAZOLOPYRIDINE KINASE INHIBITORS | MAP3K5, MAP3K20, MAP3K1 | PRKCQ 41/4885PRKCD 111/4885PRKCA 29/4885 |
| US-20190192509-A1 | Stem Cell Modulation II | PRKCQ, PRKCI, PRKCG | PRKCQ 1/4885PRKCD 9/4885PRKCA 6/4885 |
| US-20160354367-A1 | Stem Cell Modulation II | PRKCQ, PRKCI, PRKCG | PRKCQ 1/4885PRKCD 9/4885PRKCA 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.