Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004393 | 0.90 | MEN1 (0.40) | KDM4EALDH1A1CNR2HTTSMN1; SMN2 | |
| SCHEMBL7997067 | 0.89 | GSK3B (0.39) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8004439 | 0.88 | KDM4E (0.42) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8001709 | 0.88 | KDM4E (0.42) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7997782 | 0.85 | GSK3B (0.39) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8001210 | 0.84 | KDM4E (0.42) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27413865 | 0.83 | GSK3B (0.38) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8001220 | 0.83 | KDM4E (0.43) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8001338 | 0.83 | KDM4E (0.40) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6579035 | 0.82 | NPC1 (0.46) | GSK3BKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |