Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999736 | 0.83 | GSK3B (0.39) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6579035 | 0.82 | NPC1 (0.46) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8004439 | 0.81 | KDM4E (0.42) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8001709 | 0.81 | KDM4E (0.42) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7997067 | 0.81 | GSK3B (0.39) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6582560 | 0.78 | ALDH1A1 (0.46) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6581314 | 0.78 | KDM4E (0.41) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6581007 | 0.77 | ALDH1A1 (0.46) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7997782 | 0.77 | GSK3B (0.39) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8001220 | 0.77 | KDM4E (0.43) | GSK3BKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1158265-C | Quinoline ketone derivant and antianaphylaction using same as active substance | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-07-21 | — | — | CN | disclosed |
| CN-1095834-C | Quinolinone derivatives and antiallergic agent containing said quinolinone derivatives as active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2002-12-11 | — | — | CN | disclosed |
| CN-1275564-A | Quinoline ketone derivant and antianaphylaction using same as active substance | DAINIPPON INK & CHEMICALS (JP) | 2000-12-06 | — | — | CN | disclosed |
| CN-1163268-A | Quinolinone derivatives and antiallergic agent containing said quinolinone derivatives as active ingredient | LAINIPPON INK AND CHEMICALC IN (JP) | 1997-10-29 | — | — | CN | disclosed |