Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.64 |
| ▸ | F2 | P00734 | 8/20 | 0.53 |
| ▸ | PLG | P00747 | 2/20 | 0.53 |
| ▸ | PROC | P04070 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999873 | 0.98 | F10 (0.61) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8003260 | 0.95 | F10 (0.58) | F10F2PLGPROCPRSS1 | |
| SCHEMBL1652295 | 0.91 | F10 (0.56) | F10F2 | |
| SCHEMBL7986939 | 0.91 | F10 (0.66) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8003156 | 0.89 | F10 (0.61) | F10F2PLGPROCPRSS1 | |
| SCHEMBL1651311 | 0.89 | F10 (0.65) | F10F2PLGPROCPRSS1 | |
| SCHEMBL7997641 | 0.88 | F10 (0.58) | F10F2PLGPROCPRSS1 | |
| Hydrochloric Acid SCHEMBL6896958 | 0.88 | F10 (0.61) | F10F2PLGPROCPRSS1 | |
| SCHEMBL1303308 | 0.86 | F10 (0.71) | F10F2 | |
| SCHEMBL7069988 | 0.86 | F10 (0.59) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | claimed |
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |