Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.61 |
| ▸ | F2 | P00734 | 7/20 | 0.52 |
| ▸ | PLG | P00747 | 2/20 | 0.51 |
| ▸ | PROC | P04070 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999856 | 0.98 | F10 (0.64) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8003260 | 0.93 | F10 (0.58) | F10F2PLGPROCPRSS1 | |
| SCHEMBL1652295 | 0.92 | F10 (0.56) | F10F2KDM4ETSHR | |
| SCHEMBL1651311 | 0.90 | F10 (0.65) | F10F2PLGPROCPRSS1 | |
| SCHEMBL7986939 | 0.89 | F10 (0.66) | F10F2PLGPROCPRSS1 | |
| SCHEMBL8003156 | 0.89 | F10 (0.61) | F10F2PLGPROCPRSS1 | |
| SCHEMBL1303308 | 0.88 | F10 (0.71) | F10F2 | |
| Hydrochloric Acid SCHEMBL6896958 | 0.88 | F10 (0.61) | F10F2PLGPROCPRSS1 | |
| Hydrochloric Acid SCHEMBL6895022 | 0.87 | F10 (0.70) | F10F2 | |
| SCHEMBL7997641 | 0.86 | F10 (0.58) | F10F2PLGPROCPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |