Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.52 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001432 | 0.93 | IDO1 (0.48) | IDO1HDAC3EP300KAT2BKAT8 | |
| Putrescine SCHEMBL7991111 | 0.91 | IDO1 (0.57) | IDO1HDAC3EP300KAT2BKAT8 | |
| SCHEMBL29702452 | 0.82 | IDO1 (0.73) | IDO1HDAC3EP300KAT2BKAT8 | |
| SCHEMBL29393764 | 0.82 | IDO1 (0.73) | IDO1HDAC3EP300KAT2BKAT8 | |
| SCHEMBL8371459 | 0.82 | IDO1 (0.73) | IDO1HDAC3EP300KAT2BKAT8 | |
| SCHEMBL8006509 | 0.82 | IDO1 (0.73) | IDO1HDAC3EP300KAT2BKAT8 | |
| SCHEMBL485855 | 0.82 | IDO1 (0.73) | IDO1HDAC3EP300KAT2BKAT8 | |
| SCHEMBL29706585 | 0.80 | IDO1 (0.70) | IDO1HDAC3EP300KAT2BKAT8 | |
| Hydrochloric Acid SCHEMBL28651123 | 0.80 | IDO1 (0.70) | IDO1HDAC3EP300KAT2BKAT8 | |
| Ammonia Solution, Strong SCHEMBL2208087 | 0.80 | IDO1 (0.70) | IDO1HDAC3EP300KAT2BKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |