SCHEMBL7999980

SCHEMBL7999980

Clc1nc(Cl)nc(Cl)n1.NCc1ccc(O)cc1.NCc1ccc(O)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABAT P80404 1/20 0.70
TAAR1 Q96RJ0 4/20 0.46
SLC6A2 P23975 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HTR1A P08908 1/20 0.46
ADRA2A P08913 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTR3A P46098 1/20 0.46
BACE1 P56817 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
BLM P54132 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ENPP2 Q13822 1/20 0.43
ESR1 P03372 3/20 0.42
ESR2 Q92731 2/20 0.42
HRH3 Q9Y5N1 1/20 0.42
IDO1 P14902 2/20 0.41
MAOB P27338 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyramine SCHEMBL8001418 0.91 TAAR1 (0.64) ABATTAAR1SLC6A2KDM4EALDH1A1
Tyramine SCHEMBL8003312 0.85 TAAR1 (0.56) ABATTAAR1SLC6A2KDM4EALDH1A1
Tyramine SCHEMBL8002976 0.83 TAAR1 (0.72) ABATTAAR1SLC6A2KDM4EALDH1A1
SCHEMBL63123 0.83
SCHEMBL7991430 0.82 ABAT (0.47) ABATTAAR1ALDH1A1KMT2AESR1
Hydrochloric Acid SCHEMBL920435 0.81 ABAT (0.94) ABATTAAR1SLC6A2KDM4EALDH1A1
Water SCHEMBL8381326 0.81 ABAT (0.94) ABATTAAR1SLC6A2KDM4EALDH1A1
Bromide SCHEMBL3539884 0.81 ABAT (0.94) ABATTAAR1SLC6A2KDM4EALDH1A1
SCHEMBL20696075 0.81 ABAT (0.94) ABATTAAR1SLC6A2KDM4EALDH1A1
SCHEMBL27558427 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117996-A COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS NOVO NORDISK A/S (DK) 2000-09-12 US disclosed