Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000417 | 0.87 | MEN1 (0.34) | GAANPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL8002706 | 0.86 | LSS (0.34) | RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL7470125 | 0.85 | VNN1 (0.34) | NPC1 | |
| SCHEMBL8002443 | 0.84 | MAPT (0.34) | SMN1; SMN2 | |
| SCHEMBL8001979 | 0.83 | SRD5A2 (0.40) | TP53KMT2ASMN1; SMN2 | |
| SCHEMBL7990339 | 0.83 | PARP1 (0.34) | RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL8002345 | 0.82 | AR (0.30) | — | |
| SCHEMBL8002387 | 0.82 | HTT (0.47) | GAANPC1TP53RAB9AKMT2A | |
| SCHEMBL7999035 | 0.82 | KMT2A (0.34) | NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL7839566 | 0.82 | KMT2A (0.39) | TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | disclosed |