Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 7/20 | 0.40 |
| ▸ | SELE | P16581 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CDC25C | P30307 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995368 | 0.86 | SELP (0.53) | MEN1KMT2ASELPSELEPTPN1 | |
| SCHEMBL8000298 | 0.86 | SELP (0.53) | MEN1KMT2ASELPSELEPTPN1 | |
| SCHEMBL7997425 | 0.84 | MEN1 (0.46) | MEN1KMT2ASELPSELEPTPN1 | |
| SCHEMBL7997432 | 0.84 | MEN1 (0.46) | MEN1KMT2ASELPSELEPTPN1 | |
| SCHEMBL8001395 | 0.82 | MEN1 (0.54) | MEN1KMT2ASELPSELEPTPN1 | |
| SCHEMBL8194911 | 0.80 | SELP (0.58) | MEN1KMT2ASELPSELEPTPN1 | |
| SCHEMBL8194916 | 0.80 | SELP (0.58) | MEN1KMT2ASELPSELEPTPN1 | |
| SCHEMBL7853844 | 0.79 | CYSLTR2 (0.42) | SELPPTPN1LTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL7853842 | 0.79 | CYSLTR2 (0.42) | SELPPTPN1LTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL7997394 | 0.78 | MEN1 (0.49) | MEN1KMT2ASELPSELEPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033836-A9 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORP (US) | 2001-10-04 | — | — | WO | disclosed |