Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995368 | 0.85 | SELP (0.53) | MEN1KMT2APTPN1MPOP2RY12 | |
| SCHEMBL8000298 | 0.85 | SELP (0.53) | MEN1KMT2APTPN1MPOP2RY12 | |
| SCHEMBL8000357 | 0.83 | KMT2A (0.52) | MEN1KMT2APTPN1MPOP2RY12 | |
| SCHEMBL8001391 | 0.83 | KMT2A (0.52) | MEN1KMT2APTPN1MPOP2RY12 | |
| SCHEMBL8000346 | 0.82 | MEN1 (0.47) | MEN1KMT2APTPN1MPOP2RY12 | |
| SCHEMBL8194916 | 0.80 | SELP (0.58) | MEN1KMT2APTPN1MPOP2RY12 | |
| SCHEMBL8194911 | 0.80 | SELP (0.58) | MEN1KMT2APTPN1MPOP2RY12 | |
| SCHEMBL7993106 | 0.79 | MEN1 (0.54) | MEN1KMT2APTPN1MPOP2RY12 | |
| SCHEMBL7993112 | 0.79 | MEN1 (0.54) | MEN1KMT2APTPN1MPOP2RY12 | |
| SCHEMBL7997394 | 0.78 | MEN1 (0.49) | MEN1KMT2APTPN1MPOP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033836-A9 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORP (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2000033836-A1 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |