Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | TPH1 | P17752 | 8/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15760890 | 1.00 | PDCD1 (0.56) | PDCD1CD274LDHATPH1SLC7A5 | |
| SCHEMBL6339536 | 1.00 | PDCD1 (0.56) | PDCD1CD274LDHATPH1SLC7A5 | |
| SCHEMBL8009937 | 0.86 | LDHA (0.73) | LDHATPH1SLC7A5KDM4ETDP1 | |
| SCHEMBL31242504 | 0.86 | LDHA (0.73) | LDHATPH1SLC7A5KDM4ETDP1 | |
| SCHEMBL30013904 | 0.86 | LDHA (0.73) | LDHATPH1SLC7A5KDM4ETDP1 | |
| SCHEMBL159001 | 0.86 | LDHA (0.73) | LDHATPH1SLC7A5KDM4ETDP1 | |
| SCHEMBL159000 | 0.86 | LDHA (0.73) | LDHATPH1SLC7A5KDM4ETDP1 | |
| SCHEMBL29637606 | 0.86 | LDHA (0.73) | LDHATPH1SLC7A5KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL10464213 | 0.85 | LDHA (0.71) | LDHATPH1SLC7A5KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL3207583 | 0.85 | LDHA (0.71) | LDHATPH1SLC7A5KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850316-A4 | CRYPTOPHYCINS FROM ABERRANT BIOSYNTHESIS | UNIV HAWAII (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0850316-A1 | CRYPTOPHYCINS FROM ABERRANT BIOSYNTHESIS | UNIVERSITY OF HAWAII (US) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997008334-A1 | CRYPTOPHYCINS FROM ABERRANT BIOSYNTHESIS | UNIVERSITY OF HAWAII (US) | 1997-03-06 | — | — | WO | disclosed |