Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 13/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.53 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000500 | 1.00 | PIM1 (0.57) | PIM1PIM2HPGDCISD1FOXM1 | |
| SCHEMBL7987959 | 0.89 | HPGD (0.62) | PIM1PIM2HPGDCISD1 | |
| SCHEMBL7996933 | 0.89 | HPGD (0.62) | PIM1PIM2HPGDCISD1 | |
| SCHEMBL7996857 | 0.84 | HPGD (0.71) | PIM1PIM2HPGDCISD1 | |
| SCHEMBL7996853 | 0.84 | HPGD (0.71) | PIM1PIM2HPGDCISD1 | |
| SCHEMBL7987897 | 0.84 | HPGD (0.67) | PIM1PIM2HPGDCISD1 | |
| SCHEMBL7987900 | 0.84 | HPGD (0.67) | PIM1PIM2HPGDCISD1 | |
| SCHEMBL7998307 | 0.82 | HPGD (0.59) | PIM1PIM2HPGDCISD1 | |
| SCHEMBL7998309 | 0.82 | HPGD (0.59) | PIM1PIM2HPGDCISD1 | |
| SCHEMBL7998391 | 0.80 | ALDH1A1 (0.43) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |