Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008647 | 1.00 | L3MBTL1 (0.37) | L3MBTL1LMNAKDM4EALDH1A1POLB | |
| SCHEMBL7998449 | 0.99 | L3MBTL1 (0.38) | L3MBTL1LMNAKDM4EALDH1A1POLB | |
| SCHEMBL8008303 | 0.97 | L3MBTL1 (0.38) | L3MBTL1LMNAKDM4EALDH1A1POLB | |
| SCHEMBL8009276 | 0.87 | L3MBTL1 (0.34) | L3MBTL1LMNAKDM4EALDH1A1POLB | |
| SCHEMBL7998444 | 0.83 | L3MBTL1 (0.32) | L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL7998577 | 0.82 | L3MBTL1 (0.32) | L3MBTL1LMNAKDM4EALDH1A1POLB | |
| SCHEMBL8000609 | 0.80 | L3MBTL1 (0.33) | L3MBTL1LMNAKDM4EALDH1A1POLB | |
| SCHEMBL10260285 | 0.78 | NAMPT (0.33) | LMNAPOLBTHRBMTNR1AMTNR1B | |
| SCHEMBL10262128 | 0.78 | NAMPT (0.33) | LMNAPOLBTHRBMTNR1AMTNR1B | |
| SCHEMBL10292808 | 0.77 | SMN1; SMN2 (0.34) | ALDH1A1POLBMTNR1AMTNR1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134987-A1 | DIFLUOROMETHYL-CONTAINING MACROCYCLIC COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-05 | — | — | WO | disclosed |