Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998792 | 0.91 | GSK3B (0.42) | GSK3BABL1ADRA2ACNR2PGR | |
| SCHEMBL7988963 | 0.91 | GSK3B (0.42) | GSK3BABL1ADRA2ACNR2PGR | |
| SCHEMBL6582077 | 0.91 | GSK3B (0.42) | GSK3BABL1ADRA2ACNR2PGR | |
| SCHEMBL8004498 | 0.90 | GSK3B (0.40) | GSK3BTERTABL1ADRA2AKDM4E | |
| SCHEMBL7988882 | 0.90 | GSK3B (0.40) | GSK3BTERTABL1ADRA2ACNR2 | |
| SCHEMBL7988965 | 0.88 | GSK3B (0.40) | GSK3BTERTABL1CNR2KDM4E | |
| SCHEMBL8004860 | 0.87 | GSK3B (0.46) | GSK3BABL1ADRA2AKDM4EALDH1A1 | |
| SCHEMBL8000840 | 0.86 | GSK3B (0.38) | GSK3BTERTABL1ADRA2AKDM4E | |
| SCHEMBL7988841 | 0.86 | KDM4E (0.41) | GSK3BCNR2PGRRORARORC | |
| SCHEMBL7998926 | 0.86 | ABL1 (0.38) | GSK3BTERTABL1ADRA2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |