Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998193 | 0.88 | ABL1 (0.34) | GSK3BABL1TERTATMADRA2A | |
| SCHEMBL8000873 | 0.86 | GSK3B (0.40) | GSK3BABL1TERTADRA2AKDM4E | |
| SCHEMBL8001306 | 0.86 | AR (0.34) | GSK3BABL1TERTATMADRA2A | |
| SCHEMBL7988882 | 0.85 | GSK3B (0.40) | GSK3BABL1TERTADRA2AKDM4E | |
| SCHEMBL8004498 | 0.85 | GSK3B (0.40) | GSK3BABL1TERTADRA2AKDM4E | |
| SCHEMBL8001531 | 0.85 | TERT (0.32) | GSK3BABL1TERTATMADRA2A | |
| SCHEMBL7997498 | 0.85 | AR (0.35) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7997504 | 0.84 | AR (0.35) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7988965 | 0.83 | GSK3B (0.40) | GSK3BABL1TERTKDM4EALDH1A1 | |
| SCHEMBL8004860 | 0.83 | GSK3B (0.46) | GSK3BABL1ADRA2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |