Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.43 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | UNG | P13051 | 3/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998822 | 1.00 | AR (0.43) | ARGPR17UNGSERPINE1PSEN1 | |
| SCHEMBL8001562 | 0.94 | AR (0.45) | ARGPR17UNGSERPINE1ALDH1A1 | |
| SCHEMBL7997203 | 0.94 | AR (0.45) | ARGPR17UNGSERPINE1ALDH1A1 | |
| SCHEMBL8001153 | 0.93 | AR (0.44) | ARGPR17UNGSERPINE1GHSR | |
| SCHEMBL7998801 | 0.93 | AR (0.44) | ARGPR17UNGSERPINE1GHSR | |
| SCHEMBL7988485 | 0.93 | AR (0.44) | ARGPR17UNGSERPINE1GHSR | |
| SCHEMBL8004560 | 0.89 | AR (0.47) | ARGPR17UNGSERPINE1PSEN1 | |
| SCHEMBL7997292 | 0.86 | AR (0.43) | ARGPR17UNGSERPINE1ALDH1A1 | |
| SCHEMBL7998867 | 0.86 | AR (0.43) | ARGPR17UNGSERPINE1ALDH1A1 | |
| SCHEMBL7997659 | 0.86 | GAA (0.41) | ARGPR17UNGSERPINE1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |