Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29642005 | 1.00 | HDAC1 (0.53) | HDAC1HDAC3HDAC2MAPK1HDAC10 | |
| Propane SCHEMBL17594228 | 0.95 | HDAC1 (0.50) | HDAC1HDAC3HDAC2MAPK1HDAC10 | |
| SCHEMBL6418936 | 0.86 | NPC1 (0.59) | MAPK1NPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL31174164 | 0.84 | HDAC3 (0.64) | HDAC1HDAC3HDAC2MAPK1HDAC10 | |
| SCHEMBL3071688 | 0.84 | HDAC3 (0.64) | HDAC1HDAC3HDAC2MAPK1HDAC10 | |
| SCHEMBL13068319 | 0.83 | HDAC3 (0.55) | HDAC1HDAC3HDAC2MAPK1HDAC10 | |
| SCHEMBL10024769 | 0.83 | CDC25B (0.48) | NPC1RAB9ATDP1ALDH1A1KDM4E | |
| SCHEMBL15938389 | 0.81 | HDAC1 (0.53) | HDAC1HDAC3HDAC2MAPK1HDAC10 | |
| SCHEMBL17847690 | 0.81 | HDAC1 (0.53) | HDAC1HDAC3HDAC2MAPK1HDAC10 | |
| SCHEMBL959541 | 0.81 | NPC1 (0.77) | MAPK1NPC1RAB9ASIGMAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090509-A | Solution for making photoconductive layers and their electrophotographical manufacturing in CRTs | ORION ELECTRIC CO., LTD. (KR) | 2000-07-18 | — | — | US | claimed |
| WO-1998024111-A1 | A SOLUTION FOR MAKING PHOTOCONDUCTIVE LAYERS AND THEIR ELECTROPHOTOGRAPHICAL MANUFACTURING IN CRTS | ORION ELECTRIC CO., LTD. (KR) | 1998-06-04 | — | — | WO | claimed |
| EP-3765552-B1 | CATIONIC POLYMERS FOR USE AS ANION EXCHANGE POLYELECTROLYTES | 3M INNOVATIVE PROPERTIES CO (US) | 2022-05-04 | — | — | EP | disclosed |
| CN-111116451-A | Polysubstituted tryptophane benzamide compound and preparation method and application thereof | 宁波大学 | 2020-05-08 | — | — | CN | disclosed |
| EP-2953457-B1 | ERK INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2020-04-08 | — | — | EP | disclosed |
| US-9980964-B2 | ERK inhibitors and uses thereof | CELGENE CAR LLC (BM) | 2018-05-29 | — | — | US | disclosed |
| US-9796700-B2 | ERK inhibitors and uses thereof | CELGENE CAR LLC (BM) | 2017-10-24 | — | — | US | disclosed |
| US-20170210729-A1 | ERK INHIBITORS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2017-07-27 | — | — | US | disclosed |
| US-20170137406-A1 | ERK INHIBITORS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2017-05-18 | — | — | US | disclosed |
| US-9561228-B2 | ERK inhibitors and uses thereof | CELGENE AVILOMICS RESEARCH, INC. (US) | 2017-02-07 | — | — | US | disclosed |
| US-9504686-B2 | ERK inhibitors and uses thereof | CELGENE AVILOMICS RESEARCH, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| WO-2014124230-A2 | ERK INHIBITORS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2014-08-14 | — | — | WO | disclosed |
| EP-2691424-A1 | POLYMERIZABLE MONOMER, POLYMERIC COMPOUND, CHARGE CONTROL AGENT CONTAINING THE POLYMERIC COMPOUND, AND DEVELOPER BEARING MEMBER AND TONER WHICH CONTAIN THE CHARGE CONTROL AGENT | Canon Kabushiki Kaisha (JP) | 2014-02-05 | — | — | EP | disclosed |
| WO-2012133881-A1 | POLYMERIZABLE MONOMER, POLYMERIC COMPOUND, CHARGE CONTROL AGENT CONTAINING THE POLYMERIC COMPOUND, AND DEVELOPER BEARING MEMBER AND TONER WHICH CONTAIN THE CHARGE CONTROL AGENT | CANON KABUSHIKI KAISHA (JP) | 2012-10-04 | — | — | WO | disclosed |
| US-6090509-A | Solution for making photoconductive layers and their electrophotographical manufacturing in CRTs | ORION ELECTRIC CO., LTD. (KR) | 2000-07-18 | — | — | US | disclosed |
| US-6090509-A | Solution for making photoconductive layers and their electrophotographical manufacturing in CRTs | ORION ELECTRIC CO., LTD. (KR) | 2000-07-18 | — | — | US | disclosed |
| WO-1998024111-A1 | A SOLUTION FOR MAKING PHOTOCONDUCTIVE LAYERS AND THEIR ELECTROPHOTOGRAPHICAL MANUFACTURING IN CRTS | ORION ELECTRIC CO., LTD. (KR) | 1998-06-04 | — | — | WO | disclosed |
| US-4018814-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-19 | — | — | US | disclosed |
| US-4013676-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3996247-A | ANTHELMINTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137406-A1 | ERK INHIBITORS AND USES THEREOF | MAP3K20, MAP3K1, MAPK3 | HDAC1 789/4885HDAC3 770/4885HDAC2 976/4885 |
| US-20170210729-A1 | ERK INHIBITORS AND USES THEREOF | MAP3K20, MAP3K1, MAPK3 | HDAC1 789/4885HDAC3 770/4885HDAC2 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.